Mouse Glrx3 activation kit by CRISPRa

CAT#: GA205282

Glrx3 CRISPRa kit - CRISPR gene activation of mouse glutaredoxin 3



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Glrx3
Locus ID 30926
Kit Components

GA205282G1, Glrx3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205282G2, Glrx3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205282G3, Glrx3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_023140, NM_001348093
Synonyms PICOT; Txnl2
Summary Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (By similarity). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (PubMed:16809552, PubMed:18258855, PubMed:18929570). Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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