Mouse Glrx3 activation kit by CRISPRa
CAT#: GA205282
Glrx3 CRISPRa kit - CRISPR gene activation of mouse glutaredoxin 3
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Glrx3 |
Locus ID | 30926 |
Kit Components | GA205282G1, Glrx3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205282G2, Glrx3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205282G3, Glrx3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_023140, NM_001348093 |
Synonyms | PICOT; Txnl2 |
Summary | Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (By similarity). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (PubMed:16809552, PubMed:18258855, PubMed:18929570). Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN506538 | Glrx3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |