Mouse Shroom3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Shroom3
Locus ID	27428
Kit Components	GA205172G1, Shroom3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205172G2, Shroom3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205172G3, Shroom3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077595, NM_001077596, NM_015756
Synonyms	AL022960; D5Ertd287e; Shrm; Shrm3
Summary	Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.[UniProtKB/Swiss-Prot Function]

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