Mouse Hsd17b6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hsd17b6
Locus ID	27400
Kit Components	GA205152G1, Hsd17b6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205152G2, Hsd17b6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205152G3, Hsd17b6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013786, NM_001359377
Synonyms	17betaHSD9; Hsd17b9; Rdh8
Summary	NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro).[UniProtKB/Swiss-Prot Function]

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