Mouse Sh2d2a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sh2d2a
Locus ID	27371
Kit Components	GA205131G1, Sh2d2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205131G2, Sh2d2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205131G3, Sh2d2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025571, NM_021309
Synonyms	Lad; Ribp; Tsad
Summary	Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in p56-LCK-mediated T-cell signaling. Could be involved in the regulation of responses to T-cell activation stimuli, specifically proliferation and lymphokine production. Interactions with ITK and TXK may provide important biochemical links of these two important kinases with other components in the T-cell activation machinery.[UniProtKB/Swiss-Prot Function]

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