Mouse Mixl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mixl1
Locus ID	27217
Kit Components	GA205101G1, Mixl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205101G2, Mixl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205101G3, Mixl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013729
Synonyms	Mm1; Mml
Summary	Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression.[UniProtKB/Swiss-Prot Function]

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