Mouse Azi2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Azi2
Locus ID	27215
Kit Components	GA205099G1, Azi2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205099G2, Azi2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205099G3, Azi2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001048146, NM_001286507, NM_001286508, NM_013727
Synonyms	AA410145; AZ2
Summary	Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.[UniProtKB/Swiss-Prot Function]

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