Mouse Dbf4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dbf4
Locus ID	27214
Kit Components	GA205098G1, Dbf4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205098G2, Dbf4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205098G3, Dbf4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190717, NM_013726
Synonyms	AA545217; Ask
Summary	Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role DNA in replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.[UniProtKB/Swiss-Prot Function]

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