Mouse Trpc7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trpc7
Locus ID	26946
Kit Components	GA205057G1, Trpc7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205057G2, Trpc7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205057G3, Trpc7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302372, NM_001302373, NM_012035
Synonyms	TRP7; Trrp8
Summary	The protein encoded by this gene is a member of the transient receptor potential channel family of proteins, which form six-transmembrane cation-permeable channels that are calcium permeant. Knock out mice are viable but display a reduction in the gamma wave activity that precedes seizure induction in response to a muscrarinic agonist, suggesting a functional role for this protein in initiation of seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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