Mouse Slc27a2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc27a2
Locus ID	26458
Kit Components	GA204990G1, Slc27a2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204990G2, Slc27a2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204990G3, Slc27a2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011978
Synonyms	ACSVL1; FATP2; Vlac; Vlacs; VLCS
Summary	Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precursors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism (By similarity). May be involved in translocation of long-chain fatty acids (LFCA) across membranes.[UniProtKB/Swiss-Prot Function]

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