Mouse Slc27a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc27a1
Locus ID	26457
Kit Components	GA204989G1, Slc27a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204989G2, Slc27a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204989G3, Slc27a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011977, NM_001357180, NM_001357181, NM_001357182
Synonyms	Fatp; FATP1
Summary	Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane (PubMed:7954810, PubMed:9786857, PubMed:9671728, PubMed:10471110, PubMed:12235169, PubMed:11970897, PubMed:15699031, PubMed:28178239). Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (PubMed:10593920, PubMed:12235169, PubMed:12937175). May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation (PubMed:14991074, PubMed:15897321). Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis (PubMed:12235169). May be involved in regulation of cholesterol metabolism (PubMed:12235169).[UniProtKB/Swiss-Prot Function]

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