Mouse Uts2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Uts2
Locus ID	24111
Kit Components	GA204904G1, Uts2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204904G2, Uts2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204904G3, Uts2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011910
Synonyms	prepro-UII; Ucn2; UII
Summary	This gene encodes a member of the urotensin family of peptide hormones. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone before secretion into the plasma. Mice lacking the encoded protein have a significantly decreased low density lipoprotein cholesterol profile and hepatic steatosis that is consistent with decreased hepatocyte de novo cholesterol synthesis and apolipoprotein B secretion. [provided by RefSeq, Sep 2016]

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