Mouse Ik activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ik
Locus ID	24010
Kit Components	GA204860G1, Ik gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204860G2, Ik gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204860G3, Ik gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011879
Synonyms	MuRED
Summary	Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1.[UniProtKB/Swiss-Prot Function]

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