Mouse Pacsin2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pacsin2
Locus ID	23970
Kit Components	GA204844G1, Pacsin2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204844G2, Pacsin2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204844G3, Pacsin2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159509, NM_001159510, NM_011862, NM_001358641, NM_001358642, NM_001358643, NM_001358644
Synonyms	AI197433
Summary	Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.[UniProtKB/Swiss-Prot Function]

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