Mouse Grem2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grem2
Locus ID	23893
Kit Components	GA204804G1, Grem2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204804G2, Grem2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204804G3, Grem2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011825
Synonyms	Gremlin2; Prdc
Summary	Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.[UniProtKB/Swiss-Prot Function]

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