Mouse Dido1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dido1
Locus ID	23856
Kit Components	GA204784G1, Dido1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204784G2, Dido1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204784G3, Dido1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291432, NM_001291433, NM_011805, NM_175551, NM_177852, NR_111965
Synonyms	6720461J16Rik; D130048F08Rik; DATF-1; Datf1; dido; DIO-1
Summary	This gene encodes a transcription factor involved in apoptosis. The encoded protein functions in cell cycle progression and plays a role in chromosomal stability. This protein regulates the self-renewal of embryonic stem cells. Disruption of this gene in mice causes symptoms similar to myelodysplastic/myeloproliferative diseases in humans. Mice lacking this gene show severely reduced fertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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