Mouse Def8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Def8
Locus ID	23854
Kit Components	GA204782G1, Def8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204782G2, Def8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204782G3, Def8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001253783, NM_001253784, NM_001281803, NM_054046, NR_045593
Synonyms	AI449518; D8Ertd713e; DEF-8
Summary	Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:27777970). Involved in bone resorption (PubMed:27777970).[UniProtKB/Swiss-Prot Function]

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