Mouse Zpr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zpr1
Locus ID	22687
Kit Components	GA204698G1, Zpr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204698G2, Zpr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204698G3, Zpr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011752
Synonyms	AI303781; Zfp259; Znf259
Summary	Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death.[UniProtKB/Swiss-Prot Function]

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