Mouse Wt1 activation kit by CRISPRa

CAT#: GA204648

Wt1 CRISPRa kit - CRISPR gene activation of mouse Wilms tumor 1 homolog



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Wt1
Locus ID 22431
Kit Components

GA204648G1, Wt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204648G2, Wt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204648G3, Wt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_144783
Synonyms D630046I19Rik; Wt-1
Summary This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the orthologous human gene is mutated in a small subset of patients with Wilm's tumors. Alternative splicing has been noted for this gene, however, the full-length nature of these variants is not known. The mRNA for this gene has been shown to initiate translation from non-AUG (CUG) and AUG translation start sites, resulting in different isoforms. [provided by RefSeq, Apr 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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