Mouse Wnt2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wnt2
Locus ID	22413
Kit Components	GA204636G1, Wnt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204636G2, Wnt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204636G3, Wnt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023653
Synonyms	2610510E18Rik; Int1l1; Irp; Mirp; Wnt-2; Wnt2a
Summary	Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:19686689). Functions as upstream regulator of FGF10 expression (PubMed:19686689). Plays an important role in embryonic lung development (PubMed:19686689). May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (PubMed:20018874).[UniProtKB/Swiss-Prot Function]

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