Mouse Ush2a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ush2a
Locus ID	22283
Kit Components	GA204562G1, Ush2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204562G2, Ush2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204562G3, Ush2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021408
Synonyms	A930011D15Rik; A930037M10Rik; Gm676; Gm983; Mush2a; Usherin; Ushrn
Summary	Involved in hearing and vision as member of the USH2 complex (PubMed:20502675). In the inner ear, required for the maintenance of hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells (PubMed:20502675, PubMed:24334608). In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport (PubMed:20502675).[UniProtKB/Swiss-Prot Function]

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