Mouse Unc13b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Unc13b
Locus ID	22249
Kit Components	GA204544G1, Unc13b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204544G2, Unc13b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204544G3, Unc13b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081413, NM_001310758, NM_021468
Synonyms	Munc13-1; Munc13-2; Unc13a; Unc13h1; Unc13h2
Summary	Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) (By similarity). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.[UniProtKB/Swiss-Prot Function]

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