Mouse Ubp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ubp1
Locus ID	22221
Kit Components	GA204524G1, Ubp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204524G2, Ubp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204524G3, Ubp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083319, NM_013699
Synonyms	Cp2b; LBP-1a; LBP-1b; NF2d9
Summary	Functions as a transcriptional activator in a promoter context-dependent manner. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Functions as a trans-acting factor that regulates the domestic strain CYP2D9 gene through specific association with the regulatory element SDI-A1. Binding to SDI-A1 depends on the type of nucleotide at position 299; binding is abolished by a nucleotide substitution at this position. Modulates the placental expression of CYP11A1 (By similarity).[UniProtKB/Swiss-Prot Function]

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