Mouse Tub activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tub
Locus ID	22141
Kit Components	GA204487G1, Tub gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204487G2, Tub gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204487G3, Tub gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021885
Synonyms	rd5
Summary	Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight. Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages (By similarity).[UniProtKB/Swiss-Prot Function]

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