Mouse Ttf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttf1
Locus ID	22130
Kit Components	GA204482G1, Ttf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204482G2, Ttf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204482G3, Ttf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009442
Synonyms	AV245725; TTF-1; TTF-I
Summary	Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.[UniProtKB/Swiss-Prot Function]

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