Mouse Tnfsf10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfsf10
Locus ID	22035
Kit Components	GA204440G1, Tnfsf10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204440G2, Tnfsf10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204440G3, Tnfsf10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009425
Synonyms	A330042I21Rik; AI448571; APO-2L; Ly81; TL2; Tnlg6a; Trail
Summary	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.[UniProtKB/Swiss-Prot Function]

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