Mouse Tpm2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tpm2
Locus ID	22004
Kit Components	GA204425G1, Tpm2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204425G2, Tpm2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204425G3, Tpm2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001277875, NM_001277876, NM_009416
Synonyms	Tpm-2; Trop-2
Summary	This gene belongs to the tropomyosin family which encodes proteins that bind to actin filaments and stabilize them by regulating access to actin modifying proteins. The encoded protein is a high molecular weight tropomyosin expressed in slow skeletal muscle. In humans, mutations in this gene are associated with nemaline myopathy, cap disease and distal arthrogryposis syndromes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]

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