Mouse Dedd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dedd
Locus ID	21945
Kit Components	GA204400G1, Dedd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204400G2, Dedd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204400G3, Dedd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001128609, NM_011615, NM_001357550, NM_001357551, NM_001357552, NM_001357553
Synonyms	CASP8IP1; Dedpro1; DEFT; FLDED1; KE05
Summary	A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3 (By similarity). Inhibits DNA transcription in vitro.[UniProtKB/Swiss-Prot Function]

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