Mouse Tnfrsf1b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfrsf1b
Locus ID	21938
Kit Components	GA204393G1, Tnfrsf1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204393G2, Tnfrsf1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204393G3, Tnfrsf1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011610
Synonyms	CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2; TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80
Summary	Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity).[UniProtKB/Swiss-Prot Function]

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