Mouse Tle3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tle3
Locus ID	21887
Kit Components	GA204366G1, Tle3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204366G2, Tle3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204366G3, Tle3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083927, NM_001083928, NM_009389
Synonyms	2610103N05Rik; ESG; Grg3a; Grg3b; mKIAA1547
Summary	Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity). May play an important role during spermatogenesis.[UniProtKB/Swiss-Prot Function]

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