Mouse Tfdp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tfdp1
Locus ID	21781
Kit Components	GA204310G1, Tfdp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204310G2, Tfdp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204310G3, Tfdp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291765, NM_001291766, NM_001291768, NM_009361, NM_001358991
Synonyms	Dp1; Drtf1
Summary	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).[UniProtKB/Swiss-Prot Function]

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