Mouse Taf1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Taf1a
Locus ID	21339
Kit Components	GA204198G1, Taf1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204198G2, Taf1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204198G3, Taf1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001277957, NM_001277958, NM_001277959, NM_021466
Synonyms	mTAFI48; TAFI48
Summary	Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits (By similarity).[UniProtKB/Swiss-Prot Function]

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