Mouse Suclg2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Suclg2
Locus ID	20917
Kit Components	GA204160G1, Suclg2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204160G2, Suclg2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204160G3, Suclg2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001326558, NM_011507
Synonyms	AF171077; AW556404; D6Wsu120e; G-SCS; GTPSCS; SCS-betaG
Summary	GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.[UniProtKB/Swiss-Prot Function]

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