Mouse Sucla2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sucla2
Locus ID	20916
Kit Components	GA204159G1, Sucla2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204159G2, Sucla2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204159G3, Sucla2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011506, NM_001361638
Synonyms	4930547K18Rik; A-SCS
Summary	ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.[UniProtKB/Swiss-Prot Function]

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