Mouse Stac activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Stac
Locus ID	20840
Kit Components	GA204116G1, Stac gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204116G2, Stac gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204116G3, Stac gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001324546, NM_016853
Summary	Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity (PubMed:27149520). Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity (PubMed:29467163). Slows the rate of calcium-mediated inactivation of CACNA1C calcium channel activity (PubMed:29363593).[UniProtKB/Swiss-Prot Function]

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