Mouse Serpina3g activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Serpina3g
Locus ID	20715
Kit Components	GA204061G1, Serpina3g gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204061G2, Serpina3g gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204061G3, Serpina3g gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009251, NM_001353612, NM_001353613
Synonyms	2A2; AI119734; spi2; Spi2-1; Spi2/eb.1; Spi2A
Summary	Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.