Mouse Spam1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spam1
Locus ID	20690
Kit Components	GA204047G1, Spam1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204047G2, Spam1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204047G3, Spam1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001079875, NM_009241
Synonyms	AV039194; Ph-20
Summary	Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.[UniProtKB/Swiss-Prot Function]

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