Mouse Sos1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sos1
Locus ID	20662
Kit Components	GA204023G1, Sos1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204023G2, Sos1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204023G3, Sos1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009231
Synonyms	4430401P03Rik; 9630010N06; AI449023
Summary	Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (By similarity). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (PubMed:10499589, PubMed:11524436).[UniProtKB/Swiss-Prot Function]

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