Mouse Skil activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Skil
Locus ID	20482
Kit Components	GA203921G1, Skil gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203921G2, Skil gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203921G3, Skil gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039090, NM_001271772, NM_011386
Synonyms	Skir; sno; SnoN
Summary	This gene encodes a member of a small family of proteins that play a key role in the response of cells to extracellular growth signals. The encoded protein regulates members of the transforming growth factor beta signaling pathway. It is highly expressed in certain cancer cells, where it may have both tumor-suppressing and tumor-promoting roles. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

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