Mouse Six5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Six5
Locus ID	20475
Kit Components	GA203916G1, Six5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203916G2, Six5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203916G3, Six5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011383
Synonyms	Dmahp; MDMAHP; TrexBF
Summary	Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3.[UniProtKB/Swiss-Prot Function]

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