Mouse Tra2b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tra2b
Locus ID	20462
Kit Components	GA203905G1, Tra2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203905G2, Tra2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203905G3, Tra2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001330554, NM_001330555, NM_009186
Synonyms	5730405G21Rik; D16Ertd266e; Sfrs10; SIG-41; Silg41; TRA2beta
Summary	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA (By similarity).[UniProtKB/Swiss-Prot Function]

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