Mouse Sat1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sat1
Locus ID	20229
Kit Components	GA203767G1, Sat1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203767G2, Sat1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203767G3, Sat1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291865, NM_009121
Synonyms	AA617398; Sat; SSAT
Summary	Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine (By similarity).[UniProtKB/Swiss-Prot Function]

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