Mouse Sag activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sag
Locus ID	20215
Kit Components	GA203758G1, Sag gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203758G2, Sag gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203758G3, Sag gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009118
Synonyms	A930001K18Rik; Arr1; arrestin; Irbp
Summary	Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (PubMed:9333241, PubMed:16421323). May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (PubMed:16421323).[UniProtKB/Swiss-Prot Function]

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