Mouse Hps6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hps6
Locus ID	20170
Kit Components	GA203732G1, Hps6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203732G2, Hps6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203732G3, Hps6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_176785
Synonyms	5330434M19Rik; BLOC2; ru
Summary	May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules (By similarity). Acts as cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning (PubMed:25189619).[UniProtKB/Swiss-Prot Function]

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