Mouse Rtn3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rtn3
Locus ID	20168
Kit Components	GA203731G1, Rtn3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203731G2, Rtn3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203731G3, Rtn3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001003930, NM_001003933, NM_001003934, NM_001271486, NM_001271487, NM_053076
Synonyms	RTN3-A1
Summary	May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress (By similarity). Induces the formation of endoplasmic reticulum tubules (PubMed:24262037).[UniProtKB/Swiss-Prot Function]

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