Mouse Rfng activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rfng
Locus ID	19719
Kit Components	GA203623G1, Rfng gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203623G2, Rfng gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203623G3, Rfng gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009053
Synonyms	MGC90122
Summary	Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1 (PubMed:28089369). May be involved in limb formation and in neurogenesis (By similarity).[UniProtKB/Swiss-Prot Function]

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