Mouse Rangap1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rangap1
Locus ID	19387
Kit Components	GA203565G1, Rangap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203565G2, Rangap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203565G3, Rangap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146174, NM_011241, NM_001358622, NR_152441
Synonyms	C79654; Fug1; mKIAA1835
Summary	GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export (PubMed:18305100). Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export (By similarity). Required for postimplantation embryonic development (PubMed:8314081).[UniProtKB/Swiss-Prot Function]

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