Mouse Ptprr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptprr
Locus ID	19279
Kit Components	GA203499G1, Ptprr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203499G2, Ptprr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203499G3, Ptprr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001161837, NM_001161838, NM_001161839, NM_001161840, NM_011217, NM_001358484
Synonyms	Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR
Summary	Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Isoform gamma may have a role in patterning and cellular proliferation of skeletal elements in the precartilaginous/cartilaginous skeleton.[UniProtKB/Swiss-Prot Function]

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