Mouse Ptpre activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptpre
Locus ID	19267
Kit Components	GA203489G1, Ptpre gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203489G2, Ptpre gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203489G3, Ptpre gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001316678, NM_001316679, NM_001316680, NM_001316681, NM_011212
Synonyms	PTPe; PTPepsilon; RPTPepsilon
Summary	Isoform 1 acts as a negative regulator of insulin receptor (IR) signaling and is involved in insulin-induced glucose metabolism mainly through direct dephosphorylation and inactivation of IR in hepatocytes and liver (By similarity). Plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function.[UniProtKB/Swiss-Prot Function]

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