Mouse Ptprc activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptprc
Locus ID	19264
Kit Components	GA203486G1, Ptprc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203486G2, Ptprc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203486G3, Ptprc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111316, NM_001268286, NM_011210
Synonyms	B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; T200
Summary	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.