Mouse Pten activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pten
Locus ID	19211
Kit Components	GA203446G1, Pten gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203446G2, Pten gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203446G3, Pten gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008960
Synonyms	2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; MMAC1; TEP1
Summary	This gene encodes a phosphatase with dual activity against phospholipids and proteins, and acts as a tumor-suppressor. The protein contains four structural domains, a PIP2-binding domain, a catalytic tensin-type phosphatase domain, a C2 tensin-type domain and a PDZ-binding domain. The protein belongs to the protein tyrosine phosphatase family. Deletion of this gene in mice contribute to tumorigenesis in multiple tissues. [provided by RefSeq, Sep 2015]

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